Synthesis and optical properties of cyanine dyes with an aromatic azonia skeleton

Six cyanine dyes with an aromatic azonia skeleton (1a-f) were obtained by the reaction of chlorinated heptamethylene cyanine and 2-aminopyridine derivatives. Five of them (1a-d and 1f) emit red and near-infrared fluorescence at 600-800 nm. The fluorescent stains of living cells indicate that they ca...

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Bibliographic Details
Published inORGANIC CHEMISTRY FRONTIERS Vol. 5; no. 4; pp. 555 - 560
Main Authors Sha, Xin-Long, Niu, Jin-Yun, Sun, Ru, Xu, Yu-Jie, Ge, Jian-Feng
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 21.02.2018
Royal Society of Chemistry
Subjects
Chemistry
Chemistry, Organic
Cyanine dyes
Dye penetrants
Dyes
Fluorescence
I.R. radiation
Optical properties
Organic chemistry
Physical Sciences
Science & Technology
FLUORESCENT-PROBE
HYDROGEN-SULFIDE
CATIONS
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Summary:Six cyanine dyes with an aromatic azonia skeleton (1a-f) were obtained by the reaction of chlorinated heptamethylene cyanine and 2-aminopyridine derivatives. Five of them (1a-d and 1f) emit red and near-infrared fluorescence at 600-800 nm. The fluorescent stains of living cells indicate that they can penetrate the cell membrane, especially the hydroxyl-substituted dye (1c), it has lysosome targeting ability.
ISSN:2052-4129
2052-4110
2052-4110
DOI:10.1039/c7qo00889a