Non-specific Difense of the Inner Ear

The mechanism of non-specific defense of the inner ear against foreign bodies was invetsigated in guinea pigs. K-562 myelogenous leukemia cells were injected into the guinea pig perilymphatic space through the round window membrane. The tumor cells survived in the perilymphatic space for 24 hours bu...

Full description

Saved in:
Bibliographic Details
Published inEquilibrium Research Vol. 51; no. 2; pp. 281 - 286
Main Authors Takahashi, Kenichi, Iguchi, Hiroyoshi, Konishi, Kazuo, Takayama, Masahiro, Yamato, Fumihiro, Nakai, Yoshiaki, Yamane, Hideo, Sakamoto, Hiramori, Nakagawa, Takayuki
Format Journal Article
LanguageEnglish
Published Japan Society for Equilibrium Research 1992
Subjects
homeostasis
inner ear
K-562 cells
natural killer cells
Non-specific defense mechanism
Online AccessGet full text
ISSN0385-5716
1882-577X
DOI10.3757/jser.51.281

Cover

More Information
Summary:The mechanism of non-specific defense of the inner ear against foreign bodies was invetsigated in guinea pigs. K-562 myelogenous leukemia cells were injected into the guinea pig perilymphatic space through the round window membrane. The tumor cells survived in the perilymphatic space for 24 hours but cell multiplication did not seem to have occurred by that time. Natural killer cells could not be detected in the perilymphatic space. The survival of the tumor cells suggests that a significant and powerful non-specific defense mechanism is not active in the inner ear within 24 hours.
ISSN:0385-5716
1882-577X
DOI:10.3757/jser.51.281