Clinical commentary about foreign body complications over 20 years after polymethyl‐methacrylate face implants and control of late sequelae with Polynucleotides Highly Purified Technology (PN‐HPT®)

Introduction Mainly in the past, foreign body complications, including granuloma, were pretty frequent after semi‐permanent polymethyl‐methacrylate (PMMA) implants. Results The authors describe a twenty‐year history of recurring post‐PMMA complications interspersed by long uneventful years, with acu...

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Bibliographic Details
Published inJournal of cosmetic dermatology Vol. 21; no. 11; pp. 5537 - 5542
Main Authors Palmieri, Isabella Pia, Raichi, Mauro
Format Journal Article
LanguageEnglish
Published England 01.11.2022
Subjects
adverse events
Foreign Bodies - chemically induced
Granuloma - chemically induced
Humans
Methacrylates
PMMA
PN‐HPT
Polymethyl Methacrylate - adverse effects
polymethyl‐methacrylate microspheres
Skin
PN-HPT
adverse events
PMMA
polymethyl-methacrylate microspheres
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Summary:Introduction Mainly in the past, foreign body complications, including granuloma, were pretty frequent after semi‐permanent polymethyl‐methacrylate (PMMA) implants. Results The authors describe a twenty‐year history of recurring post‐PMMA complications interspersed by long uneventful years, with acute edematous side effects evolving into unpleasant skin dystrophia with persistent cutis laxa. The case report also discusses a simple clinical algorithm to discriminate among foreign body complications with particular attention to granulomas. Conclusions The authors conclude by discussing the benefits of the anti‐dystrophic treatment with natural‐origin remodeling PN‐HPT® (Polynucleotides Highly Purified Technology).
ISSN:1473-2130
1473-2165
DOI:10.1111/jocd.14950