Placento-Cranial Adhesion: A New Syndromic Association

Cases of placento-cranial adhesion are rare and most of them are incompatible with life. A few case reports in the literature have included such cases under the overarching rubric of amniotic band syndrome. We present autopsy findings of four cases with gestation period ranging from 16 to 21 weeks....

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Bibliographic Details
Published inJournal of fetal medicine Vol. 6; no. 2; pp. 51 - 56
Main Authors Chander, Bal, Dwivedi, Daisy, Thakur, Sita, Yadav, Suman
Format Journal Article
LanguageEnglish
Published New Delhi Springer India 01.06.2019
Thieme Medical and Scientific Publishers Pvt. Ltd
Subjects
Diagnostic Radiology
Maternal and Child Health
Medicine
Medicine & Public Health
Obstetrics/Perinatology/Midwifery
Original Article
Reproductive Medicine
Ultrasound
Fatal
Fetus
Adhesion
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Summary:Cases of placento-cranial adhesion are rare and most of them are incompatible with life. A few case reports in the literature have included such cases under the overarching rubric of amniotic band syndrome. We present autopsy findings of four cases with gestation period ranging from 16 to 21 weeks. All of them displayed placenta-cranial adhesion, low weight for gestation, absence of flat bones of skull, anencephaly, dysmorphic facial features, short umbilical cord and limb/digit amputation with oligohydrambios. Three out of four showed nasal groove. We propose that there are grounds for syndromic association of the features mentioned above. Furthermore, it is important that whenever such cases are identified termination of pregnancy should be considered. The article also underscores the importance of fetal autopsies.
ISSN:2348-1153
2348-8859
DOI:10.1007/s40556-019-00203-z