Health-related quality of life among five-year-old extremely preterm children with motor disorders
Background Motor disorders resulting from extremely preterm birth (EPT; <28 weeks' gestation) can limit daily activities, schooling and social relationships. Cerebral palsy (CP) affects about 10% of children and non-CP movement difficulties (MD) are highly prevalent, although they tend to be...
Saved in:
Published in | EUROPEAN JOURNAL OF PUBLIC HEALTH Vol. 32; no. Supplement_3; p. III413 |
---|---|
Main Authors | , , , , , , , , , |
Format | Journal Article Conference Proceeding |
Language | English |
Published |
Oxford
Oxford University Press
25.10.2022
Oxford Publishing Limited (England) |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Background
Motor disorders resulting from extremely preterm birth (EPT; <28 weeks' gestation) can limit daily activities, schooling and social relationships. Cerebral palsy (CP) affects about 10% of children and non-CP movement difficulties (MD) are highly prevalent, although they tend to be under-diagnosed, especially in children without other developmental difficulties. We investigated the association between motor disorders and health-related quality of life (HRQoL) among five-year-old children born EPT.
Methods
We included children at age five from a population-based EPT birth cohort born in 2011-2012 in 11 European countries (N = 1,021). Children without CP were classified using the Movement Assessment Battery for Children - 2nd edition as having significant MD (≤5th percentile of standardised norms) or being at risk of MD (6th-15th percentile). Parents reported on CP diagnoses and HRQoL using the Pediatric Quality of Life InventoryTM. We used linear regression to compare HRQoL scores by motor status adjusting for social characteristics.
Results
Children born EPT with CP, significant MD and at risk of MD had lower adjusted HRQoL total scores [95% confidence intervals] than those without MD: -26.1 [-31.0; -21.2], -9.1 [-12.0; -6.1] and -5.0 [-7.7; -2.3]. Decreases were greater for physical scores: -35.3 [-42.7; -27.9], -11.9 [-16.1; -7.8] and -5.4 [-9.1; -1.6] than psychosocial scores: -20.6 [-25.2; -16.0], -7.4 [-10.3; -4.5] and -4.9 [-7.6; -2.1]. These differences persisted after exclusion of children with other developmental difficulties.
Conclusions
Motor disorders among 5-year-old children born EPT were associated with lower HRQoL, even among children with less severe motor difficulties and without other developmental difficulties.
Key messages
Among five-year-old children born extremely preterm, severity level of motor disorders was associated with reductions of their health-related quality of life.
Differences persisted after exclusion of children with other developmental difficulties and among children not receiving motor-related health care services had lower health-related quality of life. |
---|---|
ISSN: | 1101-1262 1464-360X |
DOI: | 10.1093/eurpub/ckac130.249 |