Apoptotic Signal Pathways and Regulatory Mechanisms of Cancer Cells Induced by IL-24

• Published in: Wuhan University journal of natural sciences Vol. 21; no. 6; pp. 519 - 530
• Main Authors: Liu, Huilin, Chen, Jiaojiao, Jiang, Xingyan, Wang, Tao, Xie, Xiaoyuan, Hu, Hui, Yu, Fang, Wang, Xingzhi, Fan, Handong
• Format: Journal Article
• Language: English
• Published: Wuhan Wuhan University 01.12.2016; Springer Nature B.V
• Subjects: Apoptosis; Biomedical and Life Sciences; Cancer; Clusterin; Computer Science; Differentiation; Downstream effects; Effectors; Interleukin 24; JNK protein; Life Sciences; MAP kinase; Materials Science; Mda-7 protein; Melanoma; Mitochondria; Proteins; Regulatory mechanisms (biology); Review; Signal transduction; Transduction; Tumor cells; Wnt protein; β-Catenin; apoptosis; IL-24; signal pathway; tumor; Q257

The melanoma differentiation-associated gene-7（mda-7）,IL-24,has the specific functions that induce cancer cell apoptosis without doing harm to normal cells. We systematically review the apoptotic signal pathways and their regulatory mechanisms induced by Ad.IL-24 and IL-24 in diverse cancer cells. I...