Health-related quality of life following hysterectomy by vNOTES versus conventional laparoscopy

• Published in: Minimally invasive therapy and allied technologies Vol. 33; no. 4; p. 232
• Main Authors: Yıldız, Pınar, Keles, Esra, Yıldız, Gazi, Birol İlter, Pınar, Temoçin, Rezzan Berna, Kaya, Celal, Mat, Emre
• Format: Journal Article
• Language: English
• Published: England 01.08.2024
• Subjects: Adult; Female; Humans; Hysterectomy - methods; Laparoscopy - methods; Length of Stay - statistics & numerical data; Middle Aged; Operative Time; Pain, Postoperative; Prospective Studies; Quality of Life; laparoscopic hysterectomy; vNOTES; Hysterectomy
• ISSN: 1365-2931
• DOI: 10.1080/13645706.2024.2323100

To evaluate safety, efficacy, pre- and postoperative outcomes of vNOTES hysterectomy compared to conventional laparoscopic (CL) hysterectomy. This prospective study was conducted on patients who underwent CL or vNOTES hysterectomy for benign gynecological indications between January and July 2021. Sociodemographic, clinical, and surgical data were collected. Health-related quality of life (HRQoL) outcomes were evaluated using the EQ-5D-5L questionnaire. A total of 228 patients (CL vs. vNOTES: 147 vs. 81) were included. No significant differences were observed between the two groups in terms of blood loss, uterine weight, complications, length of hospital stay, and readmission rate. Patients in the vNOTES group experienced significantly less postoperative pain and required less analgesia compared to those who underwent CL hysterectomy (  < 0.001). The CL group had a shorter operative time (  < 0.001). There was a significant difference between the two groups in the EQ-5D-5L pain/discomfort dimension (  = 0.047). This research showed that vNOTES has various advantages, such as less postoperative pain, reduced analgesic usage, and better HRQoL outcomes three months after surgery.