Determination of Polyvinylpyrrolidone

A simple spectrophotometric method was developed for the quantitative estimation of polyvinylpyrrolidone in some pharmaceuticals and biological materials. The turbidity of polyvinylpyrrolidone precipitated by perchloric acid was measured turbidimetrically at 370mμ. The absorbance due to the turbidit...

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Bibliographic Details
Published inNippon Nōgeikagaku Kaishi Vol. 46; no. 5; pp. 267 - 271
Main Authors ISHIKAWA, Shikao, FURUICHI, Yukio, NAKAMURA, Shigeru
Format Journal Article
LanguageJapanese
Published Japan Society for Bioscience, Biotechnology, and Agrochemistry 1972
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Summary:A simple spectrophotometric method was developed for the quantitative estimation of polyvinylpyrrolidone in some pharmaceuticals and biological materials. The turbidity of polyvinylpyrrolidone precipitated by perchloric acid was measured turbidimetrically at 370mμ. The absorbance due to the turbidity was directly proportional to the concentration of the polymer ranging from 1 to 4mg per 100ml of the final test solution. Biological materials should be extracted by water and be pretreated with Somogyi's precipitants in order to remove interference of turbidity with other materials.
ISSN:0002-1407
1883-6844
DOI:10.1271/nogeikagaku1924.46.267