Model Studies Towards Stephaoxocanes: Construction of the 2-Oxa-4-aza- phenalene Core of Stephaoxocanidine and Eletefine
The construction of the polysubstituted 1H,3H‐2‐oxa‐4‐azaphenalene 4 by means of consecutive oxa‐Pictet−Spengler and Jackson cyclizations is reported. This compound contains the ABC ring system of the novel isoquinoline alkaloids stephaoxocanidine and eletefine, found in Stephania cepharantha and Ci...
Saved in:
Published in | European journal of organic chemistry Vol. 2003; no. 24; pp. 4731 - 4736 |
---|---|
Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Weinheim
WILEY-VCH Verlag
01.12.2003
WILEY‐VCH Verlag Wiley |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The construction of the polysubstituted 1H,3H‐2‐oxa‐4‐azaphenalene 4 by means of consecutive oxa‐Pictet−Spengler and Jackson cyclizations is reported. This compound contains the ABC ring system of the novel isoquinoline alkaloids stephaoxocanidine and eletefine, found in Stephania cepharantha and Cissampelos glaberrima. Both these species are Menispermaceæ used in folk medicine in the Far East and Brazil. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003 |
---|---|
Bibliography: | ArticleID:EJOC200300548 istex:EBEAA97E477FB0C227A5D82B69C318A953AC84C5 ark:/67375/WNG-4CSJ2ZBZ-G |
ISSN: | 1434-193X 1099-0690 |
DOI: | 10.1002/ejoc.200300548 |