Biodegradable and Dual‐Responsive Polypeptide‐Shelled Cyclodextrin‐Containers for Intracellular Delivery of Membrane‐Impermeable Cargo (Adv. Sci. 18/2021)

Dual‐Responsive Nanocontainers In article number 2100694, Bart Jan Ravoo, Volker Gerke, and co‐workers design nanocontainers based on cyclodextrin amphiphiles that are stabilized by a peptide shell and a redox‐responsive crosslinker. These dual‐responsive nanocontainers represent an efficient, biode...

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Published inAdvanced science Vol. 8; no. 18
Main Authors Kudruk, Sergej, Pottanam Chali, Sharafudheen, Linard Matos, Anna Livia, Bourque, Cole, Dunker, Clara, Gatsogiannis, Christos, Ravoo, Bart Jan, Gerke, Volker
Format Journal Article
LanguageEnglish
Published Weinheim John Wiley & Sons, Inc 22.09.2021
John Wiley and Sons Inc
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Summary:Dual‐Responsive Nanocontainers In article number 2100694, Bart Jan Ravoo, Volker Gerke, and co‐workers design nanocontainers based on cyclodextrin amphiphiles that are stabilized by a peptide shell and a redox‐responsive crosslinker. These dual‐responsive nanocontainers represent an efficient, biodegradable, and tunable system for overcoming the plasma membrane as a natural barrier for membrane‐impermeable cargo. The design was conceived by Sergej Kudruk and composed by Nina Knubel at the University of Münster.
ISSN:2198-3844
2198-3844
DOI:10.1002/advs.202170112