The OBSERVE guidelines provide refinement criteria for rodent oncology models

A consensus statement outlines the best practices to refine animal welfare in rodent models of cancer. Their adoption will allow the standardization of experimental interventions, considering the characteristics of each cancer model, thereby improving the reproducibility and translational value of d...

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Bibliographic Details
Published inNature protocols Vol. 19; no. 10; pp. 2831 - 2832
Main Authors Ritter, Amanda C., Cheleuitte-Nieves, Christopher, Lipman, Neil S.
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 09.07.2024
Nature Publishing Group
Subjects
631/67/70
692/4028/67/70
Analytical Chemistry
Animal models
Animal welfare
Best practice
Biological Techniques
Biomedical and Life Sciences
Cancer
Computational Biology/Bioinformatics
Intervention
Laboratory animals
Life Sciences
Medical research
Microarrays
News & Views
news-and-views
Oncology
Organic Chemistry
Pain
Reproducibility
Rodents
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Summary:A consensus statement outlines the best practices to refine animal welfare in rodent models of cancer. Their adoption will allow the standardization of experimental interventions, considering the characteristics of each cancer model, thereby improving the reproducibility and translational value of data obtained in rodents.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1754-2189
1750-2799
1750-2799
DOI:10.1038/s41596-024-01008-9