A convenient synthesis of some new 1, 3, 4-benzothiadiazepin-5-ones

A synthesis of new 1,3,4-benzothiadiazepin-5-ones (6a-c) has been achieved via cyclocondensation, promoted by acetic anhydride at reflux, of the corresponding acyclic 2-{[2-oxo-1-(N-arylhydrazono)propan-1-yl]mercapto}benzoic acids (4a-c). Structural assignments of the heterocyclic products (6a-c) ar...

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Bibliographic Details
Published inHeterocycles Vol. 63; no. 5; pp. 1153 - 1163
Main Authors Zahra, JA, Abu Thaher, BA, El-Abadelah, MM, Boese, R
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 01.05.2004
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
HETEROCYCLES
RING
ANTIFUNGAL ACTIVITY
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Summary:A synthesis of new 1,3,4-benzothiadiazepin-5-ones (6a-c) has been achieved via cyclocondensation, promoted by acetic anhydride at reflux, of the corresponding acyclic 2-{[2-oxo-1-(N-arylhydrazono)propan-1-yl]mercapto}benzoic acids (4a-c). Structural assignments of the heterocyclic products (6a-c) are based on analytical, spectral (IR, MS and NMR) and X-Ray crystal structure data.
ISSN:0385-5414
1881-0942
DOI:10.3987/com-03-9974