A simple and efficient synthesis of new 6-arylimino-6H-indolo[2,1-b]quinazolin-12-ones under microwave irradiation

A ring opening and selective reaction of isatoic anhydride with isatin-3-imine in the presence of catalytic amount of KF-Al2O3, a reusable catalyst, to yield a novel series of 6-aryliinino-6H-indolo[2,1-b]quinazolin-12-one under microwave irradiation, is described.

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Bibliographic Details
Published inHeterocycles Vol. 63; no. 4; pp. 791 - 795
Main Authors Azizian, J, Mohammadi, AA, Ardakani, F, Karimi, AR, Mohammadizadeh, MR
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 01.04.2004
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
FACILE SYNTHESIS
isatin-3-imine
KF-Al2O3
SOLID-PHASE SYNTHESIS
IMINES
CONDENSATION
IMINOKETENE CYCLOADDITION
6-arylimino-6H-indolo[2,1-b]quinazolin-12-one
LUOTONIN-A
regioselective
RUTECARPINE
isatoic anhydired
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Summary:A ring opening and selective reaction of isatoic anhydride with isatin-3-imine in the presence of catalytic amount of KF-Al2O3, a reusable catalyst, to yield a novel series of 6-aryliinino-6H-indolo[2,1-b]quinazolin-12-one under microwave irradiation, is described.
ISSN:0385-5414
DOI:10.3987/COM-03-9937