Syntheses of squarylium-substituted alanine and its peptide, and formation of their thin films onto a poly(3-methylthiophene)/Au electrode

• Published in: Biopolymers Vol. 47; no. 2; pp. 179 - 183
• Main Authors: Mikayama, Takeshi, Matsuoka, Hirokazu, Uehara, Kaku, Shimizu, Ikuo, Yoshikawa, Susumu
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 1998
• Subjects: non-natural amino acid; peptide; poly(3-methylthiophene); squarylium dye; thin film
• ISSN: 0006-3525; 1097-0282
• DOI: 10.1002/(SICI)1097-0282(1998)47:2<179::AID-BIP7>3.0.CO;2-R

We designed a polypeptide that behaves as a photodevice by using a non‐natural amino acid with replacement of an α‐hydrogen by a squarylium dye and succeeded in syntheses of the non‐natural amino acid derivative containing a squarylium and its peptide with trialanine Ala‐Ala‐Ala. Strong dye‐dye interactions were confirmed by absorption and CD spectra for the peptide in 2,2,2‐trifluoroethanol solution and in water suspension. The non‐natural amino acid derivative could be deposited onto a PMeT/Au electrode by the micelle disruption method. © 1998 John Wiley & Sons, Inc. Biopoly 47: 179–183, 1998