Favorable effect of voluntary exercise on bone metabolism in a rat model of ovariectomized osteoporosis

• Published in: Nihon Eiyō, Shokuryō Gakkai shi Vol. 45; no. 5; pp. 423 - 427
• Main Authors: Omi, N. (Japan Women's Univ., Tokyo), Morikawa, N, Hoshino, A, Igarashi, C, Ezawa, I
• Format: Journal Article
• Language: Japanese
• Published: Japan Society of Nutrition and Food Science 1992
• Subjects: ACTIVIDAD FISICA; ACTIVITE PHYSIQUE; Ash weight of femur; BONE DISEASES; BONES; breaking force of femur; Ca absorption; ENFERMEDADES OSEAS; HUESOS; METABOLISM; METABOLISME; METABOLISMO; OS; OSTEOPATHIE; OVARIECTOMIA; OVARIECTOMIE; OVARIECTOMY; PHYSICAL ACTIVITY; RAT; RATA; RATS
• ISSN: 0287-3516; 1883-2849
• DOI: 10.4327/jsnfs.45.423

Recently, Japan has become an aging society, increasing the importance of preventing postmenopausal osteoporosis. The present study was undertaken to determine the effect of voluntary exercise on bone metabolism in a rat model of postmenopausal osteoporosis. Eight-month-old Wistar-strain female rats were ovariectomized or given a sham operation. Thereafter, each rat group was further divided into non-exercise (control) and voluntary exercise (running) sub-groups. All rats were fed on a solid diet (1.2% Ca, 0.96% P) ad libitum for 170 days. The results obtained were as follows: Ia voluntary exercise groups within the ovariectomized and sham groups, the decrease of Ca absorption was alleviated for six months, the breaking force and Ca content of the femur increased and the ash weight of the femur were significantly higher than those in the control group. These results suggest that voluntary exercise could be effective for prevention of disturbances of bone metabolism in estrogen deficiency.