Intentional overdose and death with 3,4-methylenedioxyethamphetamine (MDEA; "Eve"): case report

We report a case of suicide following ingestion of a large dose of 3,4-methylenedioxyethamphetamine (MDEA, "Eve") in a 27-year-old woman with a history of depression. Several days before her death, she had attempted suicide with benzodiazepines resulting in a 24-hour hospital admission; at...

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Published inThe American journal of forensic medicine and pathology Vol. 19; no. 2; p. 148
Main Authors Arimany, J, Medallo, J, Pujol, A, Vingut, A, Borondo, J C, Valverde, J L
Format Journal Article
LanguageEnglish
Published United States 01.06.1998
Subjects
3,4-Methylenedioxyamphetamine - analogs & derivatives
3,4-Methylenedioxyamphetamine - metabolism
3,4-Methylenedioxyamphetamine - poisoning
Adult
Chromatography, Gas - methods
Designer Drugs - poisoning
Drug Overdose
Fatal Outcome
Female
Gas Chromatography-Mass Spectrometry
Humans
Suicide
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Summary:We report a case of suicide following ingestion of a large dose of 3,4-methylenedioxyethamphetamine (MDEA, "Eve") in a 27-year-old woman with a history of depression. Several days before her death, she had attempted suicide with benzodiazepines resulting in a 24-hour hospital admission; at that time, no physiologic abnormalities were detected. Findings on autopsy were nonspecific. Toxicologic analysis showed a high concentration of MDEA and the appearance of benzodiazepines in body fluids. Ethanol and other drugs of abuse were not found. We discuss the clinical manifestations, toxicologic syndromes, and mechanisms of death with amphetamine intoxication. MDEA intoxication in young people may result in sudden death.
ISSN:0195-7910
DOI:10.1097/00000433-199806000-00009