Conditioning allergic skin responses in humans: a controlled trial

Classical conditioning of immune responsiveness has been extensively investigated in animals, but few successful studies have been reported with humans. We report the results of a study in which an attempt was made to demonstrate conditioned alteration to an allergic skin test response in humans. Fo...

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Bibliographic Details
Published inPsychosomatic medicine Vol. 57; no. 5; p. 492
Main Authors Booth, R J, Petrie, K J, Brook, R J
Format Journal Article
LanguageEnglish
Published United States 01.09.1995
Subjects
Adult
Allergens - administration & dosage
Conditioning, Classical
Female
Humans
Male
Psychoneuroimmunology
Skin Tests
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Summary:Classical conditioning of immune responsiveness has been extensively investigated in animals, but few successful studies have been reported with humans. We report the results of a study in which an attempt was made to demonstrate conditioned alteration to an allergic skin test response in humans. For 8 of 10 trials, allergic skin tests were administered to one forearm of volunteer subjects, and saline was administered to the other forearm. For the other two trials, the test substances were covertly switched between arms, but no changes in response resulted from this maneuver that could be ascribed to conditioning.
ISSN:0033-3174
DOI:10.1097/00006842-199509000-00012