Treatment of cystic lesions of soft tissue using fibrin sealant

A new method was devised for treating 29 patients with cystic lesions of the soft tissue (popliteal cysts, bursitis, and ganglia) by injecting a fibrin sealant into the cyst after the aspiration of the contents. During the followup period (mean, 2.2 years), cysts did not recur in 22 (76%) patients....

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Bibliographic Details
Published inClinical orthopaedics and related research no. 321; p. 239
Main Authors Shigeno, Y, Harada, I, Katayama, S
Format Journal Article
LanguageEnglish
Published United States 01.12.1995
Subjects
Adolescent
Adult
Aged
Aged, 80 and over
Animals
Bursitis - pathology
Bursitis - therapy
Child
Cysts - therapy
Female
Fibrin Tissue Adhesive - therapeutic use
Granulation Tissue - cytology
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Popliteal Cyst - diagnosis
Popliteal Cyst - therapy
Rats
Rats, Wistar
Recurrence
Synovial Cyst - therapy
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Summary:A new method was devised for treating 29 patients with cystic lesions of the soft tissue (popliteal cysts, bursitis, and ganglia) by injecting a fibrin sealant into the cyst after the aspiration of the contents. During the followup period (mean, 2.2 years), cysts did not recur in 22 (76%) patients. Of the 7 patients with recurrences, 4 were treated again in the same manner and 3 of these cases have not recurred. Additionally, to investigate the healing process in cysts, fibrin sealant was injected into the space between the abdominal muscle and the peritoneum of rats. Specimens were obtained after the rats were sacrificed at 1, 2, 4, and 8 weeks after injection, and were examined histopathologically. The fibrin sealant was found to be completely resorbed and replaced with organized granulation tissue. In case of multiple failed aspirations to the cystic lesions, this new method is recommended before surgery.
ISSN:0009-921X
1528-1132
DOI:10.1097/00003086-199512000-00036