Insertion force reduction of micro-texture on 316L electrode for Parkinson’s surgery by Laser processing

• Published in: Materials today communications Vol. 31; p. 103403
• Main Authors: Pan, Chunyang, Xu, Changfeng, Zhou, Jun
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.06.2022
• Subjects: Deep brain stimulation; In vivo test; Insertion force; Microtextured needle; Deep brain stimulation; Microtextured needle; Insertion force; In vivo test
• ISSN: 2352-4928; 2352-4928
• DOI: 10.1016/j.mtcomm.2022.103403

Deep brain stimulation is an effective operation in the treatment of Parkinson's disease. In the process of treatment, the electrode needs to be inserted into the brain tissue for positioning, which will cause a certain damage and positioning deviation. The insertion force is the main factor affecting the degree of tissue damage and the accuracy of the target location. Therefore, an effective method to reduce the insertion force can reduce part of the insertion damage. In this research, the micro-texture with different spacing was made on the surface of the needle to form a super-hydrophilic surface and reduce the insertion force. The micro-textured needles after low-temperature annealing with the super-hydrophobic surface are also fabricated. The experiments of different micro-textured needle insertions with different insertion speeds in the porcine brain that were immersed into Artificial cerebrospinal fluid (aCSF) were tested. Besides, the experiments were also tested in vivo rat brains. The results showed that the insertion force of the needle both the textured needle and smooth needle increases with the increase of the speed. The super-hydrophilic textured needle with a certain spacing of 0.1 mm and 0.3 mm can effectively reduce the insertion force. The insertion force is reduced by up to 24% in the porcine brain immersed into aCSF and 14% reduction in vivo rat brain respectively. This study aims to find a way to reduce needle insertion force into the brain. Our results show that a certain spacing of the micro-textured needle will form a hydrophilic surface and reduce insertion force. The paper made different micro-texture with different spacing on the surface of the insertion needle and carried out experiments in vitro porcine brain and in vivo rat brain. The results were that a certain spacing of micro-texture needles can effectively decrease insertion force. Ratio of the textured needle insertion force to untextured needle insertion force under three insertion speeds (dry means not immersed into aCSF, LA means low-temperature annealing, ANOVA test at the level of 95% significance) [Display omitted]