The Relationship between HA-1 Compatibility and the Activation of Helper T Lymphocyte Precursors

• Published in: Immunobiology (1979) Vol. 203; no. 4; pp. 699 - 704
• Main Authors: Cukrova, V, Dobrovolna, M, Vrana, M, Dolezalova, L, Vitek, A, Loudova, M
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier GmbH 01.05.2001
• Subjects: Acute Disease; Bone Marrow Transplantation - adverse effects; Bone Marrow Transplantation - immunology; Female; Graft vs Host Disease - etiology; Hematopoietic Stem Cells - immunology; histocompatibility antigen HLA; HLA-A2 Antigen - genetics; Humans; Lymphocyte Activation; Male; Minor Histocompatibility Antigens - genetics; Minor Histocompatibility Antigens - immunology; Nuclear Family; Oligopeptides - genetics; Oligopeptides - immunology; T-Lymphocytes, Helper-Inducer - immunology; BMT; HTLp; PCR-SSP; aGVHD; mH genes

The relationship between the compatibility in minor histocompatibility HA-1 antigen and the activation of helper (IL-2 producing) T lymphocyte precursors in vitro was studied in the group of 17 HLA-A2 positive HLA identical siblings.Although the number of pairs studied is still small, no correlation...