Dual contrasting ability of NaGd0.7Eu0.3F4 nanocrystals tuned by their hydrophilic coating mode

[Display omitted] This work introduces non-covalent hydrophilic coating of NaGd0.7Eu0.3F4 nanocrystals by polylysine (PL) and polyethyleneimine (PEI) for MRI and fluorescent imaging purposes. PL- and PEI-stabilized nanocrystals exhibit high colloidal stability, cell internalization, fluorescent cont...

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Published inMendeleev communications Vol. 34; no. 5; pp. 637 - 639
Main Authors Dovzhenko, Alexey A., Betina, Anna A., Bulatova, Tatyana S., Bogachev, Nikita A., Nikiforov, Vladimir G., Voloshina, Alexandra D., Zairov, Rustem R., Mustafina, Asya R., Mereshchenko, Andrey S., Akhmadeev, Bulat S.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.09.2024
Subjects
cell internalization
contrast agent
Eu-based luminescence
fluorescent imaging
fluoride nanoparticle
hydrophilic coating
polymer
polymer
cell internalization
Eu-based luminescence
fluoride nanoparticle
fluorescent imaging
hydrophilic coating
contrast agent
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Summary:[Display omitted] This work introduces non-covalent hydrophilic coating of NaGd0.7Eu0.3F4 nanocrystals by polylysine (PL) and polyethyleneimine (PEI) for MRI and fluorescent imaging purposes. PL- and PEI-stabilized nanocrystals exhibit high colloidal stability, cell internalization, fluorescent contrasting of nuclei and cytoplasm, low cytotoxicity, and relaxivity (r1= 0.17 dm3 mmol–1 s–1 and r1 = 0.23 dm3 mmol–1 s–1).
ISSN:0959-9436
DOI:10.1016/j.mencom.2024.09.004