Quantification of Artemisia pollen deposition in the paranasal sinuses following functional endoscopic sinus surgery

• Published in: Powder technology Vol. 419; p. 118318
• Main Authors: Ma, Ruiping, Wang, Yusheng, Tian, Lin, Dong, Jingliang, Hu, Zhenzhen, Lou, Miao, Gong, Minjie, Zhang, Luyao, Wang, Botao, Yang, Feilun, Yu, Aibing, Zheng, Guoxi, Tong, Zhengbo, Zhang, Ya
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.04.2023
• Subjects: Allergen; Computational fluid dynamics-discrete phase model (CFD-DPM); Paranasal sinus; Particle deposition; Post-FESS; CFD; Post-FESS; CRS; ANOVA; Particle deposition; VAS; Computational fluid dynamics-discrete phase model (CFD-DPM); Paranasal sinus; DICOM; CFD-DPM; Allergen; FESS
• ISSN: 0032-5910; 1873-328X
• DOI: 10.1016/j.powtec.2023.118318

To provide quantification of the postoperative Artemisia pollen deposition as well as potential contribution from allergen distribution in the sinonasal cavities for patients underwent FESS. Employing the largest cohort of post-FESS patients, Artemisia pollen deposition in 16 postoperative sinonasal cavity models were analyzed. The effects of maxillary sinus ostia diameter on allergen deposition were investigated. Artemisia pollen had higher deposition in the ethmoid, maxillary and sphenoid sinuses following FESS, for example with (3.25 ± 4.14)% vs.(0.79 ± 1.34)% in the ethmoid sinus; allergen deposition increased significantly when the hydraulic diameters of maxillary sinus ostia >10 mm; post-FESS pollen deposition was seen to reduce consequently in the middle turbinate with (5.24 ± 6.92)% vs.(13.59 ± 8.98)%. Artemisia pollen could enter all sinuses following FESS and allergen deposition may contribute to the recurrence of postoperative nasosinusitis; size of the maxillary sinus ostia significantly affects the pollen deposition rate; Meanwhile, Artemisia pollen deposition in post-FESS patients is seen to reduce in the middle turbinate area when compared with healthy adults. [Display omitted] •This study quantified sinonasal particle deposition.•This study used the largest cohort of post-FESS patients to date.•Deposition of allergen particles was analyzed using a controlled parametric study.