Proteomic approaches for generating comprehensive protein interaction maps

• Published in: Targets Vol. 2; no. 3; pp. 85 - 92
• Main Authors: Auerbach, Daniel, Fetchko, Michael, Stagljar, Igor
• Format: Book Review Journal Article
• Language: English
• Published: Elsevier B.V 01.06.2003
• Subjects: mass spectrometry; protein interaction maps; protein interactions; proteome chips; proteomics; yeast two-hybrid; protein interactions; proteome chips; proteomics; Techniques & Methods; Pharmaceutical Science; yeast two-hybrid; mass spectrometry; Genetics; Biochemistry; protein interaction maps; Drug Discovery

The availability of complete genome sequences of numerous model organisms has initiated the development of new approaches in biological research to complement conventional biochemistry and genetics. In this context, high-throughput methods for detecting protein interactions, such as mass spectrometr...