Methemoglobinemia After Infusion of Ifosfamide Chemotherapy

Acute formation of methemoglobin is a life-threatening conditioncaused by multiple medications. In this article we report the firstcase of methemoglobinemia in a patient with metastatic uterineleiomyosarcoma, after infusion of ifosfamide chemotherapy. The patientrecovered after prompt diagnosis and...

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Bibliographic Details
Published inChest Vol. 118; no. 4; pp. 1208 - 1210
Main Authors Hadjiliadis, Denis, Govert, Joseph A.
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.10.2000
American College of Chest Physicians
Elsevier B.V
Subjects
Cancer
Causes of
Chemotherapy
Complications and side effects
Ifosfamide
methemoglobin
Methemoglobinemia
methylene blue
United States
methylene blue
ifosfamide
methemoglobin
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Summary:Acute formation of methemoglobin is a life-threatening conditioncaused by multiple medications. In this article we report the firstcase of methemoglobinemia in a patient with metastatic uterineleiomyosarcoma, after infusion of ifosfamide chemotherapy. The patientrecovered after prompt diagnosis and treatment of the condition. Amechanism for the formation of methemoglobin as a result of theifosfamide infusion is of fered.
ISSN:0012-3692
1931-3543
DOI:10.1378/chest.118.4.1208