IS THERE AN ASSOCIATION BETWEEN PULMONARY EMBOLISM AND THE USE OF PEG-ASPARAGINASE IN CHILDREN WITH LEUKEMIA?

We present two leukemic children who developed pulmonary thromboembolism (PTE) after using PEG-asparaginase.The first child, an eight-year-old boy, was diagnosed with T-acute lymphoblastic leukemia (ALL). The second child, a 6-year-old boy, was diagnosed with B-ALL.They developed PTE following induc...

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Published inHematology, Transfusion and Cell Therapy Vol. 45; pp. S43 - S44
Main Authors Orulluoğlu, Emine Yılmaz, Kaya, Zühre, Yazol, Merve, Turkcan, Büşra Topuz, Kayalı, Serap Kirkiz, Koçak, Ülker
Format Journal Article
LanguageEnglish
Published Elsevier España, S.L.U 01.10.2023
Elsevier
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Summary:We present two leukemic children who developed pulmonary thromboembolism (PTE) after using PEG-asparaginase.The first child, an eight-year-old boy, was diagnosed with T-acute lymphoblastic leukemia (ALL). The second child, a 6-year-old boy, was diagnosed with B-ALL.They developed PTE following induction phases of BFM protocol's.They were given PEG-asparaginase at a dose of 2500IU/m2. Heparin was succesfully used in both cases.Physician may consider prophylactic anticoagulants during induction.
ISSN:2531-1379
DOI:10.1016/j.htct.2023.09.077