The Role of Vertebral Augmentation Procedures in the Management of Multiple Myeloma

Approximately 90% of patients with multiple myeloma experience significant pain from osseous involvement during their lifetime. Untreated osseous involvement results in vertebral compression fractures, leading to negative consequences for quality of life. Vertebral augmentation procedures, including...

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Published inClinical hematology international Vol. 6; no. 1; pp. 51 - 58
Main Authors Thalambedu, Nishanth, Kamran, Mudassar, Al-Hadidi, Samer
Format Journal Article
LanguageEnglish
Published England SAABRON PRESS 2024
Subjects
Review
vertebral compression fractures
vertebroplasty
myeloma bone disease
vertebral augmentation procedures
kyphoplasty
Multiple myeloma
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Summary:Approximately 90% of patients with multiple myeloma experience significant pain from osseous involvement during their lifetime. Untreated osseous involvement results in vertebral compression fractures, leading to negative consequences for quality of life. Vertebral augmentation procedures, including percutaneous vertebroplasty and kyphoplasty, offer better and faster pain control and likely lower morbidity compared with non-operative interventions. Our review provides an up-to-date summary of the indications, contraindications, timing, outcomes, and potential complications of vertebral augmentation procedures to guide practicing oncologists in effectively managing bone disease in patients with multiple myeloma.
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ISSN:2590-0048
2590-0048
DOI:10.46989/001c.92984