Synthesis and spectroscopic studies of the pyrimidine-2(1H)thione derivatives
1,3-Diaryl-2-propen-1-ones 1 reacted with thiourea in the presence of sodium ethoxide to give 4,6-diaryl-3,4-dihydropyrimidine-2(1H)thiones 5 which upon dehydrogenation with 3 mol of ethanolic sodium ethoxide yielded the corresponding 4,6-diarylpyrimidine-2(1H)thiones 9 . The N-acetyl derivatives of...
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Published in | Canadian journal of chemistry Vol. 57; no. 20; pp. 2734 - 2742 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Ottawa, Canada
NRC Research Press
15.10.1979
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Online Access | Get full text |
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Summary: | 1,3-Diaryl-2-propen-1-ones
1
reacted with thiourea in the presence of sodium ethoxide to give 4,6-diaryl-3,4-dihydropyrimidine-2(1H)thiones
5
which upon dehydrogenation with 3 mol of ethanolic sodium ethoxide yielded the corresponding 4,6-diarylpyrimidine-2(1H)thiones
9
. The N-acetyl derivatives of the former thiones were prepared. Infrared, nuclear magnetic resonance, and ultraviolet spectral data of the above compounds were tabulated and discussed. |
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ISSN: | 0008-4042 1480-3291 |
DOI: | 10.1139/v79-442 |