Synthesis and spectroscopic studies of the pyrimidine-2(1H)thione derivatives

1,3-Diaryl-2-propen-1-ones 1 reacted with thiourea in the presence of sodium ethoxide to give 4,6-diaryl-3,4-dihydropyrimidine-2(1H)thiones 5 which upon dehydrogenation with 3 mol of ethanolic sodium ethoxide yielded the corresponding 4,6-diarylpyrimidine-2(1H)thiones 9 . The N-acetyl derivatives of...

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Bibliographic Details
Published inCanadian journal of chemistry Vol. 57; no. 20; pp. 2734 - 2742
Main Authors Al-Hajjar, Farouk H, Al-Farkh, Yusuf A, Hamoud, Hayat S
Format Journal Article
LanguageEnglish
Published Ottawa, Canada NRC Research Press 15.10.1979
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Summary:1,3-Diaryl-2-propen-1-ones 1 reacted with thiourea in the presence of sodium ethoxide to give 4,6-diaryl-3,4-dihydropyrimidine-2(1H)thiones 5 which upon dehydrogenation with 3 mol of ethanolic sodium ethoxide yielded the corresponding 4,6-diarylpyrimidine-2(1H)thiones 9 . The N-acetyl derivatives of the former thiones were prepared. Infrared, nuclear magnetic resonance, and ultraviolet spectral data of the above compounds were tabulated and discussed.
ISSN:0008-4042
1480-3291
DOI:10.1139/v79-442