Carcinosarcoma of the stomach

In the gastrointestinal tract, carcinosarcomas are most frequently seen in the esophagus. Carcinosarcoma in the stomach is a rare tumor. We report a carcinosarcoma of the antrum of stomach. The tumor was polypoid and exophytic in appearance and located in the antrum. Immunohistochemical studies show...

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Published inPathology oncology research Vol. 8; no. 4; pp. 275 - 277
Main Authors Kayaselcuk, Fazilet, Tuncer, Ilhan, Toyganözü, Yavuz, Bal, Nebil, Ozgür, Gürsel
Format Journal Article
LanguageEnglish
Published Netherlands Springer Nature B.V 2002
Subjects
Actin
Carcinoembryonic antigen
Carcinosarcoma - pathology
Carcinosarcoma - surgery
Cytokeratin
Desmin
Desmin - analysis
Gastrointestinal tract
Humans
Male
Medical research
Middle Aged
Necrosis
Oncology
Pathology
Sarcoma - chemistry
Sarcoma - pathology
Sarcoma - surgery
Smooth muscle
Stomach
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Stomach Ulcer - pathology
Stomach Ulcer - surgery
Tumors
Vimentin
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Summary:In the gastrointestinal tract, carcinosarcomas are most frequently seen in the esophagus. Carcinosarcoma in the stomach is a rare tumor. We report a carcinosarcoma of the antrum of stomach. The tumor was polypoid and exophytic in appearance and located in the antrum. Immunohistochemical studies showed positivity for cytokeratin, epithelial membrane antigen and cytoplasmic carcinoembryonic antigen in the epithelial component. Positive staining with vimentin, desmin and focal smooth muscle actin and negative staining with chromogranin were observed in spindle cells. Nuclear positive staining was observed with p53 and Ki-67 in both glandular and spindle atypical cells.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ObjectType-Report-1
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ISSN:1219-4956
1532-2807
DOI:10.1007/BF03036745