Successful treatment of recurrent pelvic desmoid tumour with tamoxifen: Case report

• Published in: Human reproduction (Oxford) Vol. 15; no. 2; pp. 311 - 313
• Main Authors: Chao, An-Shine, Lai, Chyong-Huey, Hsueh, Swei, Chen, Chih-Shou, Yang, Yuh-Cheng, Soong, Yung-Kuei
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.02.2000
• Subjects: Adult; Antineoplastic Agents, Hormonal - therapeutic use; Ascites - drug therapy; desmoid tumour; Female; Fibromatosis, Abdominal - diagnostic imaging; Fibromatosis, Abdominal - drug therapy; Humans; Pelvic Neoplasms - diagnostic imaging; Pelvic Neoplasms - drug therapy; Recurrence; tamoxifen; Tamoxifen - therapeutic use; Tomography, X-Ray Computed; tamoxifen; desmoid tumour
• ISSN: 0268-1161; 1460-2350; 1460-2350
• DOI: 10.1093/humrep/15.2.311

The case report of a young woman with recurrent pelvic desmoid tumour successfully treated with tamoxifen is described. The desmoid tumour recurred within 6 months after the initial exploratory laparotomy. Tamoxifen therapy led to complete relief of ascites within 2 months and complete tumour regression by the end of the fourth month, and the patient has remained stable for 6 years. Without sacrificing pelvic organs or major vessels and preserving reproductive ability, tamoxifen should be considered as the first drug of choice in such a recurrent condition.