Familial Profile of Pediatric and Adult Patients With Congenital Heart Disease in Heart Transplantation

Congenital heart disease is the most common birth defect, and heart transplantation is the main treatment of choice. As genetic causes can be identified in a considerable proportion of cases, investigation of possible family cardiac history is essential. We analyzed the profiles of pediatric heart t...

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Published inTransplantation proceedings Vol. 56; no. 5; pp. 1110 - 1111
Main Authors Hama, Flávia Misawa, Jatene, Marcelo Biscegli, Siqueira, Adailson, Krieger, José Eduardo, Azeka, Estela
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.06.2024
Subjects
Adolescent
Adult
Child
Child, Preschool
Female
Heart Defects, Congenital - genetics
Heart Defects, Congenital - surgery
Heart Transplantation - adverse effects
Humans
Infant
Male
Retrospective Studies
Young Adult
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Summary:Congenital heart disease is the most common birth defect, and heart transplantation is the main treatment of choice. As genetic causes can be identified in a considerable proportion of cases, investigation of possible family cardiac history is essential. We analyzed the profiles of pediatric heart transplant recipients in terms of family history of heart disease. This single-center retrospective study included pediatric patients who underwent heart transplantation at a tertiary hospital between 2013 and 2023. Out of 170 patients, 13 had a family history relevant to congenital heart disease, with an emphasis on the etiology of dilated cardiomyopathy and the occurrence of the same heart disease in siblings. These results can impact the management of patients with congenital heart disease.
Bibliography:ObjectType-Article-1
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ISSN:0041-1345
1873-2623
1873-2623
DOI:10.1016/j.transproceed.2024.05.004