Antioxidant activities of methanol extracts of Curculigo pilosa rhizome and Gladilous psittascinus corm against lipid peroxidation in rat's liver and heart

Antioxidant activities of methanol extracts of the rhizome of Curculigo pilosa (CP) and corm of Gladiolus psittacinus (GP) were determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging effect, reducing power, total antioxidant capacity (TAC), total phenolics content (TPC), and total flavonoi...

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Published inJournal of herbs, spices & medicinal plants Vol. 25; no. 1; pp. 1 - 10
Main Authors Karigidi, Kayode Olayele, Ojebode, Mojisola Esther, Anjorin, Oluwasegun Joseph, Omiyale, Benjamin Olusola, Olaiya, Charles Ojo
Format Journal Article
LanguageEnglish
Published Philadelphia Taylor & Francis 02.01.2019
Taylor & Francis Ltd
Subjects
Antioxidants
Cardiac glycosides
Corms
Curculigo
Flavonoids
Glycosides
Heart
Lipid peroxidation
Lipids
Liver
Malondialdehyde
Methanol
Peroxidation
Rhizomes
Saponins
Scavenging
Sodium
Sodium nitroprusside
Steroid hormones
Steroids
Tannins
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Summary:Antioxidant activities of methanol extracts of the rhizome of Curculigo pilosa (CP) and corm of Gladiolus psittacinus (GP) were determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging effect, reducing power, total antioxidant capacity (TAC), total phenolics content (TPC), and total flavonoid content (TFC). Lipid peroxidation was induced by sodium nitroprusside (SNP) in the liver and heart of healthy Wistar albino rats (in vitro) and peroxidation was monitored by malondialdehyde (MDA) content. Phytochemical screening showed the presence of tannins, steroids, and flavonoids in CP rhizomes and saponins and cardiac glycosides in GP corms. The results showed that CP possessed higher TPC, TFC, and TAC than GP and higher DPPH scavenging and reducing power activities. CP and GP inhibited the production of MDA in SNP-incubated heart and liver homogenates in a dose-dependent manner. However, the methanol extracts of the CP rhizomes showed higher reduction in MDA content than the corms of GP.
ISSN:1049-6475
1540-3580
DOI:10.1080/10496475.2018.1510457