Effect of TDM on Frequency of Digoxin Toxicity

Therapeutic drug monitoring (TDM) was instituted as a routine task in our hospital from 1985. Examination of the frequency of digoxin toxicity was conducted during the 9-year period from 1985 to 1993. Though the frequency was about 8% in 1985 and 1896, however, it gradually decreased every year to t...

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Bibliographic Details
Published inByōin yakugaku Vol. 21; no. 2; pp. 105 - 108
Main Authors UENO, KAZUYUKI, UCHIMI, YORIKO, ISHIDA, YASUHARU, YAMAGUCHI, RIYO, KATO, MOTOICHI, ARIMOTO, JUNJI, SUZUKI, YOSHIO, KOYAMA, MICHIKO, BITO, KEIZO, KONISHI, TOMOTSUGU
Format Journal Article
LanguageEnglish
Japanese
Published Japanese Society of Pharmaceutical Health Care and Sciences 1995
Subjects
digoxin
frequency
TDM
toxicity
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Summary:Therapeutic drug monitoring (TDM) was instituted as a routine task in our hospital from 1985. Examination of the frequency of digoxin toxicity was conducted during the 9-year period from 1985 to 1993. Though the frequency was about 8% in 1985 and 1896, however, it gradually decreased every year to the level of about 1% for the last two years. This suggests that TDM is an effective measure for decreasing the frequency of digoxin toxicity.
ISSN:0389-9098
2185-9477
DOI:10.5649/jjphcs1975.21.105