γ-Glutamyltranspeptidase and pH based "AND" logic gate fluorescent probe for orthotopic breast tumor imaging

An "AND" logic gate-based NIR fluorescent probe Si-NH 2 -Glu was developed based on novel meso -amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and pH dual-responsive sites. The features of Si-NH 2 -Glu enable it to be applied in orthotopic tumor imaging and fluorescence-guide...

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Published inChemical communications (Cambridge, England) Vol. 59; no. 19; pp. 2795 - 2798
Main Authors Zhang, Li-Na, Zhang, Hong, Chen, Shan-Yong, Liu, Yan-Zhao, Yang, Xiao-Hua, Xiang, Fei-Fan, Liu, Yan-Hong, Li, Kun, Yu, Xiao-Qi
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 02.03.2023
Subjects
Breast Neoplasms
Female
Fluorescent Dyes
Fluorescent indicators
gamma-Glutamyltransferase
Humans
Hydrogen-Ion Concentration
Logic circuits
Optical Imaging - methods
Rhodamine
Tumors
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Abstract An "AND" logic gate-based NIR fluorescent probe Si-NH 2 -Glu was developed based on novel meso -amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and pH dual-responsive sites. The features of Si-NH 2 -Glu enable it to be applied in orthotopic tumor imaging and fluorescence-guided surgery. Combining γ-glutamyl transpeptidase and pH dual-responsive sites, an "and" logic gate-based NIR fluorescent probe Si-NH 2 -Glu was developed for orthotopic breast tumor imaging.
AbstractList An "AND" logic gate-based NIR fluorescent probe Si-NH 2 -Glu was developed based on novel meso -amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and pH dual-responsive sites. The features of Si-NH 2 -Glu enable it to be applied in orthotopic tumor imaging and fluorescence-guided surgery. Combining γ-glutamyl transpeptidase and pH dual-responsive sites, an "and" logic gate-based NIR fluorescent probe Si-NH 2 -Glu was developed for orthotopic breast tumor imaging.
An "AND" logic gate-based NIR fluorescent probe Si-NH2-Glu was developed based on novel -amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and pH dual-responsive sites. The features of Si-NH2-Glu enable it to be applied in orthotopic tumor imaging and fluorescence-guided surgery.
An “AND” logic gate-based NIR fluorescent probe Si-NH2-Glu was developed based on novel meso-amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and pH dual-responsive sites. The features of Si-NH2-Glu enable it to be applied in orthotopic tumor imaging and fluorescence-guided surgery.
An “AND” logic gate-based NIR fluorescent probe Si-NH2-Glu was developed based on novel meso -amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and pH dual-responsive sites. The features of Si-NH2-Glu enable it to be applied in orthotopic tumor imaging and fluorescence-guided surgery.
An "AND" logic gate-based NIR fluorescent probe Si-NH2-Glu was developed based on novel meso-amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and pH dual-responsive sites. The features of Si-NH2-Glu enable it to be applied in orthotopic tumor imaging and fluorescence-guided surgery.An "AND" logic gate-based NIR fluorescent probe Si-NH2-Glu was developed based on novel meso-amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and pH dual-responsive sites. The features of Si-NH2-Glu enable it to be applied in orthotopic tumor imaging and fluorescence-guided surgery.
Author Yu, Xiao-Qi
Li, Kun
Chen, Shan-Yong
Zhang, Hong
Liu, Yan-Zhao
Xiang, Fei-Fan
Zhang, Li-Na
Yang, Xiao-Hua
Liu, Yan-Hong
AuthorAffiliation Department of Chemistry
Ministry of Education
College of Chemistry
Xihua University
Sichuan University
Key Laboratory of Green Chemistry and Technology
Asymmetric Synthesis and Chiral Technology Key Laboratory of Sichuan Province
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Snippet An "AND" logic gate-based NIR fluorescent probe Si-NH 2 -Glu was developed based on novel meso -amine Si-Rhodamine, which combined γ-glutamyl transpeptidase...
An “AND” logic gate-based NIR fluorescent probe Si-NH2-Glu was developed based on novel meso -amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and...
An "AND" logic gate-based NIR fluorescent probe Si-NH2-Glu was developed based on novel -amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and pH...
An “AND” logic gate-based NIR fluorescent probe Si-NH2-Glu was developed based on novel meso-amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and...
An "AND" logic gate-based NIR fluorescent probe Si-NH2-Glu was developed based on novel meso-amine Si-Rhodamine, which combined γ-glutamyl transpeptidase and...
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SubjectTerms Breast Neoplasms
Female
Fluorescent Dyes
Fluorescent indicators
gamma-Glutamyltransferase
Humans
Hydrogen-Ion Concentration
Logic circuits
Optical Imaging - methods
Rhodamine
Tumors
Title γ-Glutamyltranspeptidase and pH based "AND" logic gate fluorescent probe for orthotopic breast tumor imaging
URI https://www.ncbi.nlm.nih.gov/pubmed/36789681
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