Comparing the Fatty Acid Composition and Neuroprotective Effects of Some Lamiaceae Taxa from Turkey

• Published in: Chemistry of natural compounds Vol. 58; no. 2; pp. 208 - 212
• Main Authors: Fafal, Tugce, Kaftan, Gizem, Tastan, Pelin, Kivcak, Bijen, Armagan, Guliz
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.03.2022; Springer; Springer Nature B.V
• Subjects: Analysis; Cell death; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Composition; Fatty acids; Hydrogen peroxide; Organic Chemistry; Plant Sciences; Toxicity; Unsaturated fatty acids; Turkey; fatty acids; neuroprotection
• ISSN: 0009-3130; 1573-8388
• DOI: 10.1007/s10600-022-03642-9

This study aims to analyze the fatty acid composition and neuroprotective potential of some selected Lamiaceae taxa from Turkey. For this purpose, methanol extracts of Lamium album L., Lamium garganicum L., Phlomis rigida Labill., Salvia syriaca L., Salvia sclarea L., and Stachys cretica subsp. anatolica Rech. f. were investigated for their activity against hydrogen peroxide induced neuronal cell death. The fatty acid compositions were analyzed by GC-FID, and the IA and IT indices and the ω3/ω6 ratio were also calculated. Saturated and unsaturated fatty acids of selected Lamiaceae species were measured to range from 8.92–17.59% and 75.13–84.57%, respectively. Phlomis rigida with the highest ω3/ω6 was shown to have the highest neuroprotection against H 2 O 2 -induced cell toxicity.