Assessment of Sleep Disorders in Children with Transfusion-Dependent Hemoglobinopathies

• Published in: Annals of child neurology Vol. 31; no. 3; pp. 189 - 196
• Main Authors: Ali, Ahmed Masoud, Mohamed, Ahmad Darwish, Elbilsha, Mona Ahmed
• Format: Journal Article
• Language: English
• Published: Korean Child Neurology Society 01.07.2023; 대한소아신경학회
• Subjects: anemia, sickle cell; hemoglobinopathies; sleep wake disorders; thalassemia; 신경과학
• ISSN: 2635-909X; 2635-9103
• DOI: 10.26815/acn.2023.00045

Purpose: The aim of this study was to compare sleep problems between children with transfusion-dependent hemoglobinopathies and healthy controls.Methods: This study was a case-control survey of children with transfusion-dependent hemoglobinopathies. The sample consisted of 175 children in the patient group and 175 healthy children in the control group, with an age range of 8 to 18 years. Subjects were recruited from the Children’s Hospital of Mansoura University between February and July 2022. Children with transfusion-dependent hemoglobinopathies received consultations at the Department of Pediatric Hematology. The Children’s Sleep Habits Questionnaire (CSHQ) was used to evaluate sleep problems in both groups.Results: The mean age of the patient group was 11.22±2.39 years, and 52.57% (n=92) were girls. The control group had a mean age of 11.30±2.16 years, and 50.86% (n=89) were boys. The overall score (P=0.007) and the night waking (P=0.013), sleep duration (P=0.009), and sleep-disordered breathing (P=0.029) subscores were all substantially and statistically significantly higher in children with transfusion-dependent hemoglobinopathies than in healthy children.Conclusion: As children with transfusion-dependent hemoglobinopathies have more sleep problems than healthy children, more detailed studies are needed.