P-C bond formation: synthesis of phosphino amino acids by palladium-catalysed cross-coupling

(4-Diethylphosphanyl)- and (4-diphenylphosphanyl)-derivatives of D- and L-phenylalanine have been synthesised using a palladium-catalysed cross-coupling giving the desired products in very high yields and without racemisation. (C) 2000 Published by Elsevier Science Ltd.

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Bibliographic Details
Published inTetrahedron: asymmetry Vol. 11; no. 7; pp. 1617 - 1621
Main Authors Kraatz, HB, Pletsch, A
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 20.04.2000
Subjects
Chemistry
Chemistry, Inorganic & Nuclear
Chemistry, Organic
Chemistry, Physical
Physical Sciences
Science & Technology
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Summary:(4-Diethylphosphanyl)- and (4-diphenylphosphanyl)-derivatives of D- and L-phenylalanine have been synthesised using a palladium-catalysed cross-coupling giving the desired products in very high yields and without racemisation. (C) 2000 Published by Elsevier Science Ltd.
ISSN:0957-4166
DOI:10.1016/S0957-4166(00)00103-8