Synthesis of Gal determinant epitopes, their glycomimetic variants, and trimeric clusters - relevance to tumor associated antigens and to discordant xenografts

The synthesis of Gal alpha1 --> 3Gal-quinic acid pseudo-trisaccharides and their elaboration into trimeric clusters is described. (C) 2001 Elsevier Science Ltd. All rights reserved.

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Bibliographic Details
Published inTetrahedron Vol. 57; no. 16; pp. 3281 - 3290
Main Authors Hanessian, S, Huynh, HK, Reddy, GV, Duthaler, RO, Katopodis, A, Streiff, MB, Kinzy, W, Oehrlein, R
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 16.04.2001
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
XENOTRANSPLANTATION
ACID
pseudo-saccharides
GLYCOSIDASE-CATALYZED SYNTHESIS
PROMOTED REACTIONS
HYPERACUTE REJECTION RESPONSE
ALPHA 1-3GAL
carbohydrate mimetics
INHIBITION
clustering
TN
B TYPE-2 TRISACCHARIDE
DERIVATIVES
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Summary:The synthesis of Gal alpha1 --> 3Gal-quinic acid pseudo-trisaccharides and their elaboration into trimeric clusters is described. (C) 2001 Elsevier Science Ltd. All rights reserved.
ISSN:0040-4020
DOI:10.1016/S0040-4020(01)00195-8