Surgical pulmonary valve replacement at a tertiary adult congenital heart centre in the current era

• Published in: International journal of cardiology congenital heart disease Vol. 9; p. 100394
• Main Authors: Kubota, Kana, Diller, Gerhard-Paul, Kempny, Aleksander, Hoschtitzky, Andreas, Imai, Yasushi, Kawada, Masaaki, Shore, Darryl, Gatzoulis, Michael A.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.09.2022; Elsevier
• Subjects: Adult congenital heart disease; Pulmonary valve replacement; Tetralogy of fallot; Pulmonary valve replacement; Adult congenital heart disease; Tetralogy of fallot
• ISSN: 2666-6685; 2666-6685
• DOI: 10.1016/j.ijcchd.2022.100394

Surgical pulmonary valve replacement (PVR) is the standard cardiac operation in adult patients with congenital heart disease (ACHD). We report recent experience at a large tertiary centre and examine the impact of prosthesis type on outcomes. All surgical PVRs performed at our tertiary centre between January 2003 and December 2018 were included. The study population included 490 patients (197 women; mean age 29.9 ± 13 years). The types of valves used were Homograft 179 (37%), Perimount 152 (31%), Mosaic 120 (24%), Hancock 31 (6%), and others 5 (1%). Seven (1.4%) early deaths occurred within 30 days after surgery. The survival rates at 1, 5, 10, and 15 years of follow-up were 98.3%, 97.7%, 96.8%, and 95.4%, respectively, whereas freedom from re-intervention was 99.8%, 96.6%, 90.2%, and 81.0%, respectively. During a mean follow-up of 6.5 ± 4.3 years, 27 (5.5%) patients required re-intervention. The type of valve used in these 27 patients during index operation showed no discernible difference in the probability of re-intervention; however, Mosaic valves required earlier re-intervention compared to Perimount valves. Our data show no discernible difference in reoperation rates between the different types of prostheses used. On-going surveillance of patients after PVR and further research in developing a life-long prosthesis are clearly warranted.