High-temperature detoxification strategy based on thermal analysis kinetics for resource utilization of biopharmaceutical waste

• Published in: Fuel (Guildford) Vol. 342; p. 127854
• Main Authors: Han, Tong, Bai, Mengyuan, Bai, Xuyang, Liu, Junjiang, Liu, Shurui, Wang, Jiabo, Wang, Yifan, Yang, Zhongyu, Duan, Erhong
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 15.06.2023
• Subjects: Biopharmaceutical waste; Chlorella growth; High-temperature detoxification strategy; Non-isothermal pyrolysis; Thermal analysis; Non-isothermal pyrolysis; Chlorella growth; Biopharmaceutical waste; Thermal analysis; High-temperature detoxification strategy
• ISSN: 0016-2361; 1873-7153
• DOI: 10.1016/j.fuel.2023.127854

[Display omitted] •Hazardous wastes were assessed by thermal analysis and Chlorella growth trends.•The violent phase change was accompanied by SO2, CO2, N2, NH3, O and H2O.•The ΔS values for three stages decreased and then increased with reaction change.•Mechanism of stage 2 was only Mampel Power rule, while values of n from 3/2 to 1.•Sodium concentration and ammonia release promoted chlorella growth at 0.24 g/L. High-temperature pyrolytic detoxification reactions based on thermal analysis facilitate the resource reuse of solid waste from the biopharmaceutical industry. This study described thermodynamic parameters, gas by-products, and safety assessment. The most common emissions (H2O, O, NH3) peak at 345–440 °C, accompanied by a shift in the micro-interfacial reaction mechanism, resulting in the largest rate of weight loss and the most significant release of gaseous by-products from the reaction. The peak CO2, SO2, and N2 emissions were dominated by deamination and sodium enrichment reactions, following the Mampel Power law mechanism. The growth trends of protein-nucleated Chlorella indicated the safety of the product at each stage. Compared to sample 375, sample 440 promoted the growth of Chlorella to a certain extent (maximum boost of 0.24 g⋅L-1⋅d-1), indicating non-toxicity and neutral pH, which may be due to a shift in pH to neutral as a result of pyrolytic detoxification, thus increasing safety and facilitating resource recovery. Possible reaction pathways for the pyrolysis of solid products were derived, and the availability of end products that contribute to the safe reuse of final value-added products from biopharmaceutical waste.