Immune-mediated necrotizing myopathy: Report of two cases
Immune-mediated necrotizing myopathy is a rare autoimmune myopathy characterized by muscle weakness and elevated serum creatine kinase, with unique skeletal muscle pathology and magnetic resonance imaging features. In this paper, two patients are reported: One was positive for anti-signal recognitio...
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| Published in | World journal of clinical cases Vol. 11; no. 15; pp. 3552 - 3559 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Baishideng Publishing Group Inc
26.05.2023
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| Subjects | |
| Online Access | Get full text |
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| Summary: | Immune-mediated necrotizing myopathy is a rare autoimmune myopathy characterized by muscle weakness and elevated serum creatine kinase, with unique skeletal muscle pathology and magnetic resonance imaging features.
In this paper, two patients are reported: One was positive for anti-signal recognition particle antibody, and the other was positive for anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody.
The clinical characteristics and treatment of the two patients were analysed, and the literature was reviewed to improve the recognition, diagnosis, and treatment of this disease. |
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| Bibliography: | Corresponding author: Huai-Qiang Hu, PhD, Doctor, Department of Neurology, The 960th Hospital of People′s Liberation Army, No. 25 Normal Road, Tianqiao District, Jinan 250031, Shandong Province, China. huhuaiqiang@126.com Author contributions: Chen BH collected and sorted out the cases, reviewed the literature, and wrote the manuscript; Xie L and Zhu XM reviewed the literature; Hu HQ reviewed and revised the manuscript; all authors have read and approved the final manuscript. |
| ISSN: | 2307-8960 2307-8960 |
| DOI: | 10.12998/wjcc.v11.i15.3552 |