Rebamipide: thirty years of experience. A review

The review article describes the 30-year practice of using the cytoprotector rebamipide. The use of the drug in South Korea and Russia in various gastrointestinal disorders, including gastroesophageal reflux disease, functional and organic dyspepsia, chronic gastritis, gastric ulcer, including those...

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Bibliographic Details
Published inTerapevtic̆eskii arhiv Vol. 96; no. 12; pp. 1217 - 1222
Main Authors Bakulina, Natalia V., Ponomarenko, Viktoriia A., Bakulin, Igor G.
Format Journal Article
LanguageRussian
Published "Consilium Medicum" Publishing house 27.12.2024
Subjects
gastrointestinal diseases
non-steroidal anti-inflammatory drugs
proton pump inhibitors
rebamipide
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Summary:The review article describes the 30-year practice of using the cytoprotector rebamipide. The use of the drug in South Korea and Russia in various gastrointestinal disorders, including gastroesophageal reflux disease, functional and organic dyspepsia, chronic gastritis, gastric ulcer, including those associated with H. pylori, inflammatory bowel diseases, irritable bowel syndrome, and as a carcinopreventive agent has been demonstrated. Particular attention is paid to drug-induced conditions, given the uncontrolled use of non-steroidal anti-inflammatory drugs and the high prevalence of cardiovascular diseases, which requires the use of antithrombotic drugs with ulcerogenic action.
ISSN:0040-3660
2309-5342
DOI:10.26442/00403660.2024.12.203041