Single high ELISA values suggest recent varicella-zoster virus infection

Sera from 383 healthy adults were examined by an ELISA procedure for varicellazoster virus (VZV) antibody and only one specimen was found with a value greater than 0.84. Clinical information from the next 51 individuals whose serum ELISA values exceeded 0.84 was evaluated. Sufficient clinical data w...

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Bibliographic Details
Published inSerodiagnosis and immunotherapy in infectious disease Vol. 2; no. 1; pp. 17 - 20
Main Author Mayo, Donald R.
Format Journal Article
LanguageEnglish
Published Oxford Elsevier B.V 1988
Butterworth-Heinemann
Subjects
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Microbiology
single high ELISA values
Techniques used in virology
varicella-zoster infection
Virology
single high ELISA values
varicella-zoster infection
Human
Varicella zoster virus
Antibody
Herpesviridae
Virological exploration
Alphaherpesvirinae
Immunological method
Infection
Virus
Viral disease
Varicella
Serum
Diagnosis
ELISA assay
Humoral immunity
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Summary:Sera from 383 healthy adults were examined by an ELISA procedure for varicellazoster virus (VZV) antibody and only one specimen was found with a value greater than 0.84. Clinical information from the next 51 individuals whose serum ELISA values exceeded 0.84 was evaluated. Sufficient clinical data was obtained for 42 of the cases. At least 39 of the 42 cases had laboratory evidence or clinical suspicion of recent VZV infection. Single ELISA values greater than 0.84, when they occur, suggest recent VZV infection.
ISSN:0888-0786
DOI:10.1016/0888-0786(88)90031-5