An efficient regioselective sonochemical synthesis of novel 4-aryl-3-methyl-4,5-dihydro-1H-pyrazolo[3,4-b]pyridin-6(7H)-ones

An efficient ultrasound-assisted preparation of a series of novel 4-aryl-3-methyl-4,5-dihydro-1H-pyrazolo[3,4-b]pyridin-6(7H)-ones via the reaction of 5-amino-3-methyl-1H-pyrazole, Meldrum's acid and various arylaldehydes using one-pot three-component approach is described. This rapid method pr...

Full description

Saved in:
Bibliographic Details
Published inChinese chemical letters Vol. 23; no. 4; pp. 399 - 402
Main Authors Roshan, Abbas Azimi, Mamaghani, Manouchehr, Mahmoodi, Nosrat Ollah, Shirini, Farhad
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.04.2012
Department of Chemistry, Faculty of Sciences, University of Guilan, P.O. Box 41335-1914, Rasht, Iran
Subjects
5-Amino-3-methylpyrazole
Meldrum's acid
One-pot
Pyrazolo[3,4-b]pyridin-6(7H)-one
Regioselective
Three-component
Ultrasonic irradiation
Regioselective
Three-component
Ultrasonic irradiation
Pyrazolo[3,4-b]pyridin-6(7H)-one
One-pot
5-Amino-3-methylpyrazole
Meldrum's acid
Online AccessGet full text

Cover

More Information
Summary:An efficient ultrasound-assisted preparation of a series of novel 4-aryl-3-methyl-4,5-dihydro-1H-pyrazolo[3,4-b]pyridin-6(7H)-ones via the reaction of 5-amino-3-methyl-1H-pyrazole, Meldrum's acid and various arylaldehydes using one-pot three-component approach is described. This rapid method produced the products in short reaction times (3–4min) and excellent yields (87–95%).
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2011.12.009