Light-dependent on/off ratio of organic photoelectrochemical transistor biosensing

• Published in: Sensors and actuators. B, Chemical Vol. 412; p. 135807
• Main Authors: Ban, Rui, Li, Cheng-Jun, Hu, Jin, Xu, Yi-Tong, Chen, Feng-Zao, Zhang, Ling, Lin, Peng, Zhao, Wei-Wei
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.08.2024
• Subjects: Biosensing; Light; On/off ratio; Organic transistors; Photoelectrochemical; Organic transistors; On/off ratio; Light; Photoelectrochemical; Biosensing
• ISSN: 0925-4005; 1873-3077
• DOI: 10.1016/j.snb.2024.135807

Organic electrochemical transistors (OECTs) possessing controllable on/off ratio (Ron/off) has long been pursued but remains challenging. Till now, few solutions to this problem are well established. Innovative light-material interactions have seen a tremendous growth in diverse electronic applications, but its possibility in Ron/off modulation has not been studied. This study addresses the challenge by the technique of organic photoelectrochemical transistor (OPECT), which is represented by metal-organic framework (MOF) derivative Ce-doped ZnIn2S4 (Ce-ZIS) gated poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) channel upon proper light impact. Interestingly, the interplay between light and Ce-ZIS could appropriately alter the device physics, rendering the light-dependent Ron/off for better transduction of biosensing signal within a fixed VG window. Biologically interfacing with a non-linear hybrid chain reaction directed dendritic DNA superstructure, the device has been shown possible for detection of microRNA-25 with good performance. •MOF derivatives Ce-doped ZnIn2S4 was prepared for light-gated organic transistor.•The light offered the device larger on/off ratio that was beneficial to bio-analysis.•The system exhibited good detection performance for the target microRNA-25.