Utility of Methicillin-Resistant Staphylococcus aureus Nasal PCR Testing in Pediatric Patients With Suspected Respiratory Infections

Observational studies in adults suggest nasal methicillin-resistant Staphylococcus aureus (MRSA) swabs have a high negative predictive value (NPV) for ruling out MRSA pneumonia, however, pediatric data are limited. This retrospective study of 505 pediatric patients found a 99.8% NPV among children w...

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Published inJournal of the Pediatric Infectious Diseases Society Vol. 13; no. 4; pp. 242 - 245
Main Authors Baker, Brooke, Hung, Frances, Smith, Michael J, Erkanli, Alaattin, Greenhill, Katherine, Hayes, Jillian, Parish, Alice, Zhou, Grace, Moorthy, Ganga S, Deri, Connor R
Format Journal Article
LanguageEnglish
Published England 24.04.2024
Subjects
Adolescent
Child
Child, Preschool
Female
Humans
Infant
Male
Methicillin-Resistant Staphylococcus aureus - genetics
Methicillin-Resistant Staphylococcus aureus - isolation & purification
Polymerase Chain Reaction - methods
Predictive Value of Tests
Respiratory Tract Infections - diagnosis
Respiratory Tract Infections - microbiology
Retrospective Studies
Staphylococcal Infections - diagnosis
Staphylococcal Infections - microbiology
de-escalation
antimicrobial stewardship
children
nasal swab
MRSA
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Summary:Observational studies in adults suggest nasal methicillin-resistant Staphylococcus aureus (MRSA) swabs have a high negative predictive value (NPV) for ruling out MRSA pneumonia, however, pediatric data are limited. This retrospective study of 505 pediatric patients found a 99.8% NPV among children with suspected respiratory infections.
Bibliography:ObjectType-Article-1
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ObjectType-Feature-2
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ISSN:2048-7207
2048-7207
DOI:10.1093/jpids/piae023