Vitamin D side chain triazole analogs via cycloaddition 'click' chemistry

Cycloaddition of a vitamin D side chain terminal acetylene with phenyl azide and separately with a vitamin D side chain terminal azide produced the corresponding 1,2,3-triazole monomeric and dimeric analogs of 1alpha-hydroxyvitamin D-3 in good yields. (C) 2004 Published by Elsevier Ltd.

Saved in:
Bibliographic Details
Published inTetrahedron letters Vol. 45; no. 24; pp. 4623 - 4625
Main Authors Suh, BC, Jeon, HB, Posner, GH, Silverman, SM
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 07.06.2004
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
INHIBITION
vitamin D
CALCIFEROL
'click' chemistry
DERIVATIVES
triazole
1-ALPHA,25-DIHYDROXYVITAMIN D-3
Online AccessGet full text

Cover

More Information
Summary:Cycloaddition of a vitamin D side chain terminal acetylene with phenyl azide and separately with a vitamin D side chain terminal azide produced the corresponding 1,2,3-triazole monomeric and dimeric analogs of 1alpha-hydroxyvitamin D-3 in good yields. (C) 2004 Published by Elsevier Ltd.
ISSN:0040-4039
DOI:10.1016/j.tetlet.2004.04.118