Synthesis of copper nanoparticles by a sonication-mediated method using Malpighia glabra fruit extract and their applications

• Published in: RSC advances Vol. 14; no. 46; pp. 34119 - 34134
• Main Authors: Nguyen, Trung Dien, Hoang, Yen Hai, Thi-Tuyet Thai, Nhung, Thi-Ngoc Trinh, Gia
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 23.10.2024; The Royal Society of Chemistry
• Subjects: Chemical synthesis; Chemistry; Copper; Copper converters; Gram-positive bacteria; Nanomaterials; Nanoparticles; Phenols; Response surface methodology; Zeta potential
• ISSN: 2046-2069; 2046-2069
• DOI: 10.1039/d4ra06087c

This study introduces an environmentally friendly technique for copper nanoparticle synthesis utilizing fruit extract under the sonication treatment. The synthesis process and phenol red removal were optimized by a central composite full and response surface design. Highly pure and spherical-shaped copper nanoparticles with an average size of 22.5 nm were formed using 7.4 mL of fruit extract and 21.9 mM (AcO) Cu. Additionally, the extract-mediated nanoparticles opposed the negative charges with a zeta potential of -11.8 mV and high stability of 30 days storage time. The sonication-assisted nanoparticles exhibited the highest inhibition against Gram-positive bacteria ( and ), MCF7 human breast cancer cells, and with 50% inhibition concentrations reaching 12, 0.82, and 80 ppm, respectively. Additionally, the green-synthesized nanomaterials functioned as an effective catalyst to remove phenol red. A conversion of 97% after a 540 seconds reaction was determined on 10 ppm phenol red with the presence of 21.5 ppm copper nanoparticles and 51.8 mM NaBH . This research highlights the potential of fruit extract in the sustainable production of copper nanoparticles, with promising applications in biomedicine, agriculture, and environmental remediation.