Synthesis of triazole-linked pseudo-oligosialic acid derivatives

Using the Cu I -catalyzed 1,3-dipolar cycloaddition of terminal alkynes to azides, neuraminic acid di-, tri-, and tetrapseudosaccharides were synthesized, in which monosaccharide residues are linked by triazole intersaccharidic bridges.

Saved in:
Bibliographic Details
Published inRussian chemical bulletin Vol. 71; no. 8; pp. 1784 - 1793
Main Authors Savelyeva, N. Yu, Shpirt, A. M., Orlova, A. V., Chizhov, A. O., Kononov, L. O.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.08.2022
Springer Nature B.V
Subjects
Alkynes
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Cycloaddition
Full Articles
Inorganic Chemistry
Monosaccharides
Organic Chemistry
Triazoles
polysialic acids
click chemistry
1,3-dipolar cycloaddition reactions
Neu5Ac
acetylneuraminic acid
Online AccessGet full text

Cover

More Information
Summary:Using the Cu I -catalyzed 1,3-dipolar cycloaddition of terminal alkynes to azides, neuraminic acid di-, tri-, and tetrapseudosaccharides were synthesized, in which monosaccharide residues are linked by triazole intersaccharidic bridges.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-022-3590-3