Differentiation of the Rat Dermatitis Factor and the Chick Dermatitis Factor from Nicotinic Acid

Data are presented to show that nicotinic acid will not cure rat dermatitis or prevent chick dermatitis, and it is concluded that vitamin B6 and the filtrate factor are both distinct from nicotinic acid. The finding of Elvehjem et al. (loc. cit.) that nicotinic acid will cure balcktongue in dogs has...

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Bibliographic Details
Published inThe Journal of nutrition Vol. 16; no. 2; pp. 183 - 195
Main Authors Dann, W.J., Subbarow, Y.
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.08.1938
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Summary:Data are presented to show that nicotinic acid will not cure rat dermatitis or prevent chick dermatitis, and it is concluded that vitamin B6 and the filtrate factor are both distinct from nicotinic acid. The finding of Elvehjem et al. (loc. cit.) that nicotinic acid will cure balcktongue in dogs has been confirmed. These results are regarded as affording direct evidence that the vitamin B2 complex contains the following four different, sharply characterized entities: riboflavin, nicotinic acid, vitamin B6 and the filtrate factor.
ISSN:0022-3166
DOI:10.1093/jn/16.2.183