A Comparative Analysis of the Effect of Intestinal Cestodes in Different Fish Species on Proteolytic Enzyme Activity

• Published in: Journal of evolutionary biochemistry and physiology Vol. 58; no. 3; pp. 644 - 651
• Main Authors: Frolova, T. V., Izvekova, G. I.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01.05.2022; Springer Nature B.V
• Subjects: Animal Physiology; Barbatula barbatula; Biochemistry; Biomedical and Life Sciences; Comparative analysis; Enzymatic activity; Evolutionary Biology; Experimental Papers; Intestine; Life Sciences; Lota lota; Mucosa; Proteinase inhibitors; Proteolysis; Proteolytic enzymes; Serine proteinase; Species; Trypsin; protease inhibitors; cestodes; proteolytic activity; fish
• ISSN: 0022-0930; 1608-3202
• DOI: 10.1134/S0022093022030024

We found that all the six cestode species, Proteocephalus torulosus (Batsch, 1786), P. sagittus (Grimm, 1872), P. cernuae (Gmelin, 1790), Eubothrium rugosum (Batsch, 1786), Triaenophorus nodulosus (Pallas, 1781), and Caryophyllaeus laticeps (Pallas, 1781), which parasitize in the intestines of fish, such as the dace Leuciscus leuciscus L., stone loach Barbatula barbatula L., ruffe Gymnocephalus cernuus L., zope Ballerus ballerus L., burbot Lota lota L., pike Esox lucius Linnaeus, and bream Abramis brama L., alter the activity of proteolytic enzymes in the host intestinal mucosa. The infestation reduced the proteolytic activity level in some host species or enhanced it in the others. Whatever the direction of these changes, all the studied tapeworms were able to inhibit mucosal protease activity (as well as that of commercial trypsin). In some cestode species, the inhibitory effect was comparable to that of the synthetic serine protease inhibitor PMSF.